Callum Ah Chee (shoulder), Alex Sexton (concussion) and Ben Ainsworth (knee) will play no further part in Gold Coast's Round 19 match against Richmond.
Ah Chee suffered a shoulder knock in the second quarter and was removed from the field with medical assistance.
Sexton was knocked to the ground during a marking contest, also in the second quarter, and has since failed concussion tests.
Ainsworth suffered a knee injury mid-way through the third term.